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P. O’Connell

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Open access Jul 2026

A human cytokine response atlas to reconstruct underlying gene regulatory networks

A single-cell atlas of approximately 10 million human peripheral blood mononuclear cells from 12 donors exposed to 90 cytokines is transformed into a multiscale model of cytokine response, and CytoCarto, a web application that projects cytokine profiles onto these networks to prioritize dysregulated programs, candidate...

P. O’Connell · 0 citations

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