Author

P. Paribello

3 papers indexed here

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Open access Sep 2026

683. Genomic foundations of precision treatment: polygenic risk and pleiotropy in predicting therapeutic response

Abstract Background Major depressive disorder (MDD) is the most common mental disorder and is associated with substantial functional impairment, socioeconomic costs and reduced quality of life. One third of patients presents treatment-resistant depression (TRD), a major clinical challenge that highly contributes to the...

C. Pisanu, Y. Xiong, D. Congiu et al. · International Journal of Neu... · 0 citations

Review Open access Jul 2026

Phthalates and Bisphenols as Endocrine-Disrupting Chemicals: Possible Determinants of Mood Disorders

Major depressive disorder (MDD) accounts for a substantial share of global disability-adjusted life years and remains inadequately treated despite pharmacological advances. Growing evidence implicates endocrine-disrupting chemicals (EDCs)—particularly phthalates and bisphenols—as environmental contributors to the onset...

M. Lastretti, Andrea Faa, Monica Piras et al. · Environments · 0 citations

#generative ai Review Open access Sep 2026

Emotional Reliance on Artificial Intelligence: A Scoping Review of AI Companionship and Mental Health Implications

Background: Artificial intelligence (AI)-driven conversational systems are increasingly capable of simulating empathy, adapting to individual users, and fostering emotional bonds that blur the boundary between tool and companion. This scoping review maps the extent and nature of published evidence regarding psychologic...

M. Lastretti, M. Manchia, Matteo Fraschini et al. · Psychiatry International · 0 citations