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Review Open access Sep 2026

Endothelial Plasticity as a Continuum in the Tumor Microenvironment.

The tumor microenvironment (TME) is a dynamic and complex ecosystem in which endothelial cells (ECs) play a central role beyond their traditional function as passive vascular conduits. Increasing evidence indicates that tumor-associated endothelial cells (TECs) undergo profound phenotypic and functional reprogramming,...

G. Rathod, P. Parmar, A. Teja · 0 citations
Review Open access Jul 2026

Estrogen receptor signaling without estrogen: molecular insights into hormone resistance

Abstract Objectives Estrogen receptor alpha (ERα) is thought to be a ligand-dependent transcription factor. Increasing number of data suggest that ERα is able to retain its transcriptional activity without stimulation by estrogen and therefore contributes to development of endocrine resistance in hormone receptor-posit...

G. Rathod, P. Parmar · 0 citations

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