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Author

P. Pattabiraman

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2 papers indexed here

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Open access Oct 2026

AKT1-phosphorylated TERT assembles a FOXO3-MYC transcriptional complex that drives ERphagy and proteostasis in post-mitotic RPE.

The retinal pigment epithelium (RPE) sustains lifelong proteostasis under chronic stress, yet how post-mitotic cells activate macroautophagy/autophagy when canonical kinase pathways suppress it remains unresolved. Here we demonstrate that AKT1 (protein kinase B alpha), drives autophagy through a non-canonical transcrip...

Vishnu Suresh Babu, Sayan Ghosh, Sridhar Bammidi et al. · 0 citations
Review Open access Aug 2026

Clusterin as a therapeutic agent: Bridging the gap in brain and eye research.

Clusterin (CLU) is a multifunctional secreted glycoprotein that is widely expressed in human tissues and body fluids. It plays critical roles in maintaining tissue homeostasis, regulating inflammation, modulating immune responses, and promoting cellular survival in both the brain and the eye. The CLU gene undergoes alt...

B. Zaman, Avinash Soundararajan, P. Pattabiraman et al. · 0 citations

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