Author

P. R. Onck

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Review Open access Sep 2026

RNA‐Protein Assemblies: A Review of Biophysical Principles and Coarse‐Grained Modeling Approaches

ABSTRACT RNA‐protein assemblies are fundamental organizers of eukaryotic cell biology, participating in diverse processes such as ribosome biogenesis in nucleoli, mRNA sequestration in nuclear speckles, and genome packaging in viral ribonucleoprotein (vRNP) complexes. Across these systems, multivalent RNA‐protein inter...

Muhammad Waleed Iqbal, P. R. Onck · Wiley Interdisciplinary Revi... · 0 citations

Open access Sep 2026

Colloidal protein stability and surface coverage by trehalose: bridging molecular dynamics and experimental work.

The aim of this study was to assess to what extent a simulated trehalose monolayer can predict the minimum molar trehalose to protein ratios required to preserve the colloidal stability of lyophilized lactate dehydrogenase, catalase, and β-galactosidase. We employed an iterative molecular dynamics (MD) approach to quan...

D. Zillen, V. Adupa, K. Nguyen et al. · European journal of pharmace... · 0 citations