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GG at the PSM independently predicts BCR, with the strongest effect in lower-grade tumors (ISUP 1-2; HR 7.08 for GG4), attenuated in high-grade disease (HR 2.98).
Available evidence does not support a strong or consistent association between dietary factors and bladder cancer (BC) risk, and patients should be informed that dietary modifications alone are unlikely to meaningfully alter their BC risk.
Growing evidence suggests that AS appears oncologically safe in well-selected patients, and magnetic resonance imaging will play a key role in the appropriate selection and follow-up of patients.
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