Author

P. Ran

3 papers indexed here

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Open access Aug 2026

Plasma metabolomic signatures enable the diagnosis and prognosis of chronic obstructive pulmonary disease

Chronic obstructive pulmonary disease (COPD) is a progressive heterogeneous lung disease driving global illness and death, yet reliable biomarkers for its early diagnosis, molecular subtyping and prognosis are lacking. Here, we conduct targeted plasma metabolomic profiling in two independent, deeply phenotyped cohorts...

Chen Li, Jie Yao, Fan Wu et al. · Nature Communications · 0 citations

Aug 2026

Association Between Respiratory Exacerbations and Accelerated Lung Function Decline in Chronic Obstructive Pulmonary Disease: A Prospective Observational Population-based Cohort Study.

BACKGROUND Moderate-to-severe and severe respiratory exacerbations in chronic obstructive pulmonary disease (COPD) accelerate lung function decline. However, whether any mild-to-severe exacerbations are associated with lung function decline in COPD remains unclear, especially in mild-to-moderate COPD and in the Global...

K. Zhou, Fan Wu, Q. Wan et al. · Respiratory Medicine · 0 citations

Review Open access Jul 2026

Association of increased depressive symptoms and lung health in participants with pre-COPD: A population-based study.

Increased depressive symptoms were associated with a higher risk of pre-COPD phenotypes, respiratory symptoms, and mortality, and may be a treatable trait that can help mitigate adverse outcomes in participants with pre-COPD.

Ke-Fan Wu, Li-Fei Lu, Yubiao Chen et al. · Pulmonology · 0 citations