Author

P. Ropero

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Sep 2026

Hemoglobin E Associated with Hemoglobin Constant Spring: Diagnostic Challenges in Heterozygous and Homozygous States.

Hemoglobin E (HbE) is a common structural hemoglobin variant with a β+-thalassemic effect. Hemoglobin Constant Spring (HbCS) is the most prevalent non-deletional α-thalassemia variant and is characterized by low expression and marked instability, making detection difficult. The coexistence of both variants may produce...

P. Ropero, S. Escribano, Mariola Abío et al. · Hemoglobin · 0 citations

Editorial Open access Aug 2026

Digital PCR‐based non‐invasive prenatal diagnosis should be considered in the evolving diagnostic pathway for sickle cell disease

We read with great interest the European Hematology Association (EHA) recommendations by de Montalembert et al. on preconceptual and antenatal screening and prenatal diagnosis for hemoglobino-pathies. The manuscript provides a timely and valuable framework for genetic counseling and reproductive decision ‐ making in th...

P. Ropero, F. González, Miguel Gómez et al. · HemaSphere · 0 citations