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Author

P. Sage

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Review Sep 2026

T follicular regulatory cell differentiation and functional states.

Follicular regulatory T (Tfr) cells enter the B-cell follicle and germinal center, where they control the magnitude, specificity, and duration of the antibody response. However, the temporal and spatial determinants of Tfr differentiation are incompletely understood. Recent advances in fate-mapping, single-cell transcr...

Jeong-Mi Lee, P. Sage · 0 citations
Open access Jul 2026

CAR19 Tregs treat murine chronic graft-versus-host disease through immune suppression without measurable B cell cytolysis

The findings suggest that CAR19 Tregs represent a promising and safe cGVHD/BOS therapeutic strategy, offering immunosuppressive benefits and improved disease outcomes that may be more limited with CD8+ CAR19 T cell treatment.

Sujeong Jin, Michael C. Zaiken, Cameron McDonald-Hyman et al. · 0 citations

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