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Open access Oct 2026

Long-term outcomes of combined significant aortic regurgitation and mitral regurgitation versus isolated aortic regurgitation

Combined aortic regurgitation (AR) and mitral regurgitation (MR) is a relatively common multiple valvular heart disease. Current guidelines recommend intervention (AVI and/or MVI) when either lesion becomes severe in the setting of symptoms, left ventricular (LV) systolic dysfunction or dilation, as in isolated s...

C. Ng, P. Santi, N. Elmasry et al. · 0 citations
Open access Oct 2026

Increased left atrial pressure in chronic aortic regurgitation: association with outcomes

Among asymptomatic patients with moderate-severe or severe chronic AR and preserved LVEF, elevated LAP is independently associated with increased long-term mortality, suggesting that markers of elevated LV filling pressures may improve risk stratification of these patients.

P. Santi, N. Elmasry, J. Bernard et al. · 0 citations
Open access Oct 2026

Left ventricular remodeling and outcome after transcatheter aortic valve implantation in patients with small aortic annulus

Comparable long-term survival was observed between SAA and No-SAA patients supporting the safety and effectiveness of TAVI in patients with SAA, and significant LV reverse remodeling and systolic functional improvement occur after TAVI regardless of aortic valve annular size.

H. Tang, P. Santi, Y. Obayashi et al. · 0 citations

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