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Author

P. Schommers

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2 papers indexed here

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Open access Sep 2026

Durable suppression of viremia by lipid nanoparticle-formulated RNA encoding for a highly potent HIV-1 neutralizing antibody

Recombinant broadly neutralizing antibodies (bNAbs) are promising tools to treat and prevent HIV-1 infection but are associated with manufacturing challenges. To overcome this limitation, we encoded the potent bNAb 1-18-LS on RNA (1-18-LS RibobNAb) for delivery via lipid nanoparticles (LNPs). Indicating high in vivo an...

Sophie Sayettat, F. Tolksdorf, Robin Johannson et al. · 0 citations
Review Open access Jul 2026

Nef as a driver of immunodeficiency and HIV-associated diseases: insights from mouse models

This review summarizes existing transgenic mouse models with cell type-specific Nef expression and humanized mouse models used in HIV research, including models based on Nef-deficient strains, to provide experimental validation for the clinical implementation of Nef inhibitors in combination with established ART.

A. Yakovleva, E. Gorshkova, E. Gubernatorova et al. · 0 citations

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