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Open access Oct 2026

Type 6 secretion systems of adherent-invasive Escherichia coli isolated from Crohn’s disease patients shape intestinal microbiota

Adherent Invasive Escherichia coli (AIEC) colonize the ileal mucosa of Crohn’s disease patients. Among bacterial virulence factors potentially implicated, type 6 secretion systems (T6SS) are molecular machineries sending effectors in prokaryotic or eukaryotic target cells. Two T6SS have been reported in AIEC LF82 refer...

Hélène Botchorichvili, S. Massier, B. Chassaing et al. · 0 citations
Sep 2026

Persistence, Safety and Pharmacokinetics of Vedolizumab After Switching to the Subcutaneous Route in a Prospective French National Cohort Study.

BACKGROUND AND AIM We conducted a prospective study to evaluate the persistence, efficacy, pharmacokinetics, and safety of subcutaneous VDZ (SC-VDZ) after switching from the intravenous (IV) route. METHODS All patients with ulcerative colitis (UC) or Crohn's disease (CD) in clinical remission who switched from IV-VDZ...

Marianne Hupé, Nicolas Mathieu, A. Amiot et al. · 0 citations

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