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P. Serruys

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Review Open access Sep 2026

Incidence and Predictors of Complications After Transcatheter Aortic Valve Implantation According to VARC-3 Criteria: A Systematic Review and Meta-Analysis.

BACKGROUND Despite continuous advancements in devices and techniques, transcatheter aortic valve implantation remains associated with complications impacting outcomes. In 2021, the Valve Academic Research Consortium (VARC) introduced the VARC-3 criteria to better classify procedural complications. METHODS We conducte...

F. Giacobbe, Francesco Bruno, M. Brero et al. · 0 citations
Review Jul 2026

Efficacy and Safety of Selective Aldosterone Synthase Inhibitors in Uncontrolled Hypertension: A Systematic Review and Dose-Specific Network Meta-Analysis of Randomized Controlled Trials.

Selective aldosterone synthase inhibitors (ASIs), including baxdrostat and lorundrostat, target CYP11B2 while sparing cortisol synthesis, offering a novel strategy for resistant and uncontrolled hypertension. Yet existing meta-analyses have included nonselective agents or omitted the latest phase 3 data. We searched Pu...

N. Hammad, M. Elkasaby, A. Gadelmawla et al. · 1 citation
Open access Sep 2026

Impact of stepwise dual antiplatelet therapy de-escalation in patients with multivessel disease undergoing drug-coated balloon angioplasty: insights from the REC-CAGEFREE II trial

Among patients with ACS undergoing DCB-only angioplasty, those with multivessel disease were associated with a higher risk of NACE than those with single-vessel disease and stepwise DAPT de-escalation and standard DAPT exhibited similar risk-benefit profiles in both subgroups.

C. Gao, Y. Zhang, X. He et al. · 0 citations
Open access Jul 2026

Validated 1-Year Mortality Prediction in Patients with Three-Vessel Disease Undergoing Contemporary PCI: Insights from the Multivessel TALENT trial.

In contemporary PCI for 3VD, the LCSS showed moderate discrimination for 1-year all-cause mortality while overestimating its absolute risk, although observed mortality increased across predicted-risk quintiles.

A. Oshima, N. Kanehama, D. van Klaveren et al. · 0 citations
Open access Jul 2026

Effect of Fluoroscopy‐Only Versus Transesophageal Echocardiography/Intracardiac Echocardiography Guidance in Left Atrial Appendage Occlusion on Stroke Prevention: Analysis From the RECORD I Study

F fluoroscopy‐only guidance, without compromising long‐term stroke prevention efficacy, may serve as a streamlined and potentially accessible alternative for left atrial appendage occlusion procedures performed with the first‐generation WATCHMAN 2.5 device.

Ping Wang, Zhengquan Chen, Yongmeng Yan et al. · 0 citations

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