Metastasis and associated therapy resistance remain the principal drivers of cancer related death, and there is a pressing need for a deeper mechanistic understanding and anti-metastatic therapies. For patients that suffer from hepatocellular carcinomas (HCCs), which are the most common primary liver cancers, frequent...
T. A. Rants'o, Kathryn Woods, Paige Jensen et al.· bioRxiv· 0 citations
SpatialMET is an open-source framework that provides an end-to-end workflow for MSI analysis that provides a unified platform for preprocessing, spatial domain detection, and visualization and is distributed as a Docker container for reproducible deployment.
Y. Mekonnen, Oscar E. Ospina, Vanessa Y. Rubio et al.· bioRxiv· 0 citations
Redox imbalances and mitochondrial dysfunction are key contributors to age‐related declines in skeletal muscle and may contribute to impaired exercise responsiveness. Here, we investigated the influence of aging on skeletal muscle redox at rest and in response to acute exercise, examining how mitochondrial quality and...
Bradley A. Ruple, Nicholas A Carlini, Jason S. Kofoed et al.· Aging Cell· 0 citations
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