Open access
Jun 2025
Plasticity in a bacterial global regulatory switch that drives a shift in antibiotic resistance and virulence
Overall, it is demonstrated the transcriptomic basis of MexT as a phenotypic switch in PAO1 and implicated antibiotic resistance as a cause of downstream changes in mexT in P. aeruginosa, confirming that PAO1 is a very different organism compared to most isolates.
Annapaula Correia, Emma J. Manners, Benjamin A. Evans et al.
· bioRxiv · 0 citations