Author

P. Thompson

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Open access Aug 2026

Interpretable multimodal learning for integrating neuroimaging and genetic data in Alzheimer’s disease

R-GenIMA, an interpretable multimodal large language model that pairs a region-of-interest vision transformer with genetic prompting to jointly analyze structural MRI and single nucleotide polymorphisms, shows that interpretable multimodal AI can integrate imaging and genetics to reveal disease mechanisms.

Kun Zhao, Si-Yuan Dai, Ying-Ying Zhang et al. · Frontiers in Radiology · 0 citations

Open access Jul 2026

Mapping Focal and Generalized Effects of Common Genetic Variants on Human Brain Structure

Brain-wide maps of polygenic scores (PGS) from loci associated with ten brain volume regions of interest reveal patterns consistent with both localized and distributed genetic influences, offering a novel approach to interpret the genomic architecture of brain structure.

Emma J Gleave, L. García-Marín, Z. Ceja et al. · bioRxiv · 0 citations