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P. Tordiglione

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Review Open access Jul 2026

The Gut–Brain Axis in Depression: A Systematic Review of Microbiota and Mental Health

Gut microbiota dysbiosis represents a biologically plausible mediator of depression pathophysiology, with a recurrent dysbiotic pattern, characterised by depletion of butyrate-producing taxa and enrichment of pro-inflammatory genera, showing emerging diagnostic and therapeutic potential.

Lorenzo Campedelli, Andrea Cicoli, M. Lastretti et al. · 0 citations