Author

P. V. van Veelen

2 papers indexed here

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Open access Jul 2026

CRISPR activation screen uncovers MARCKSL1 as a gauge for extracellular vesicle secretion.

How cells balance these competing routes using a genome-wide CRISPR activation screen for factors that alter surface expression of CD63-an EV-associated tetraspanin that shuttles between the PM and endosomes is investigated.

Yingjie Zhong, Anna E. George, Roman I. Koning et al. · Cell Reports · 0 citations

Open access Jul 2026

Identification of cellular intermediates unveils unique enzymes for flagellar glycan biosynthesis in Clostridioides difficile.

Glycosylation of bacterial surface proteins, such as flagellin (FliC), is important for their function and is often involved in virulence of pathogens. Glycans can be further modified by so-called postglycosylation modifications (PGMs), often resulting in exclusive molecular structures. In Clostridioides difficile, a u...

P. Hensbergen, Bob van Puffelen, Nina Musch et al. · Proceedings of the National... · 0 citations