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Author

P. van Damme

2 papers indexed here

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Review Open access Sep 2026

Progress towards a biotypic biomarker profile for amyotrophic lateral sclerosis-frontotemporal spectrum disorders.

Determining the optimal timing of disease-modifying therapies for neurodegenerative disorders will necessitate identification of when the underlying pathobiological process becomes active, well in advance of the point at which clinical manifestions appear. Phenoconversion, the emergence of clinically manifest syndomes,...

Michael J. Strong, Neil S. Donison, A. Al-Chalabi et al. · 0 citations
Open access Sep 2026

Towards a deep-learning genomic tool for risk stratification and diagnostic support in sporadic ALS

A variety of common and rare genetic factors have been implicated in the development of amyotrophic lateral sclerosis (ALS), and the evidence is that a genetic component is present in most affected individuals. However, our current understanding of ALS genetics causally explains only a small proportion of sporadi...

Jia-Jing Hu, Oliver Pain, A. Al Khleifat et al. · 0 citations

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