Neuroimaging is now a cornerstone of Alzheimer's disease care and a crucial discriminator tool for characterising brain injury across the lifespan and with emerging fluid biomarkers, neuroimaging supports accurate diagnosis, prognosis, and treatment monitoring.
Tammie L. S. Benzinger, P. Cogswell, A. Arani et al.· Lancet Neurology· 2 citations
Tau pathology in the presence of Aβ was a stronger predictor of cognition in ADNI than in U.S. POINTER, and this discrepancy was not explained by increased vascular risk or brain atrophy in U.S. POINTER.
Pei-Wei Liu, Theresa M. Harrison, H. Snyder et al.· NeuroImage: Clinical· 0 citations
Findings support the potential value of EOAD-signature atrophy as an MRI-based biomarker for individualized prognostication and clinical trial stratification and support the potential value of EOAD-signature atrophy as an MRI-based biomarker for individualized prognostication and clinical trial stratification.
T. Paranhos, Yuta Katsumi, M. Brickhouse et al.· Neurology· 0 citations
Generalized additive models examined clinical progression on the basis of visual and CenTauRz-based assessments of tau PET positivity and highlighted the need for new quantification approaches to better capture the complex patterns of tau deposition, important for early AD detection and monitoring.
Stamatia Karagianni, Alexis Moscoso, Sheelakumari Raghavan et al.· Journal of Nuclear Medicine· 0 citations
Findings lend support for PVS-BG as an early indicator of small vessel dysfunction and WMH pathogenesis and suggest that PVS-BG may identify individuals at increased risk of progressive SVD.
Audrey Low, J. Gunter, Ming-Zhao Hu et al.· Annals of Neurology· 0 citations
Diffusion MRI biomarkers were abnormal at least a decade before WMH abnormality in the population, revealing a prolonged phase of early SVD and highlighting their potential for SVD prevention.
P. Vemuri, Ming-Zhao Hu, Emily S. Lundt et al.· Stroke· 0 citations
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