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Author

P. Vigneri

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Open access Sep 2026

Prognostic value of hormone receptor expression in patients with HR+/HER2− advanced BC treated with first-line ET+CDK4/6i: results from the multicentre observational, real-world PALMARES-2 study

Effectiveness of first-line ET plus CDK4/6i in patients with HR+/HER2− aBC worsens progressively with decreasing ERα expression, and PgR expression adds further prognostic discrimination, with low ERα and PgR expression identifying a subgroup of patients with particularly poor outcomes.

F. Ligorio, L. Provenzano, R. Caputo et al. · 0 citations
Review Open access Jul 2026

Clinical Implications of UGT1A1 Polymorphisms in Anticancer Therapy: An Updated Review

Although substantial evidence supports the association between UGT1A1 genotype and drug safety, implementation of genotype-guided treatment remains inconsistent, and further harmonization of international recommendations, high-quality prospective studies, and wider access to pharmacogenetic testing are needed to suppor...

S. Vitale, Melissa Drago, F. Martorana et al. · 0 citations

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