Association between circulating GTP cyclohydrolase 1 concentrations and acute ischemic stroke: an exploratory case–control study in a Chinese population
Background and objective Ischemic stroke (IS) is a leading global cause of disability and mortality, characterized by cerebral hypoxia and tissue necrosis. GTP cyclohydrolase 1 (GCH1) regulates endothelial function and oxidative stress; however, whether circulating GCH1 concentrations are altered in acute ischemic stro...