Author

Pal Pacher

2 papers indexed here

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Open access Sep 2026

PCSK9 inhibition attenuates alcohol-induced cardiovascular dysfunction and links hepatic lipid accumulation to impaired myocardial contractile reserve.

Excessive alcohol consumption accelerates cardiovascular aging by promoting oxidative stress, inflammation, lipid dysregulation, fibrotic remodeling, and loss of ventricular-vascular reserve. PCSK9, a key regulator of cholesterol metabolism, has emerged as a mediator of age-related cardiovascular dysfunction and alcoho...

C. Mátyás, Eszter Trojnar, P. Mukhopadhyay et al. · GeroScience · 0 citations

Review Open access Sep 2026

Chronic Liver Disease-Related Osteoporosis: From Mechanisms to Precision Intervention.

BACKGROUND & AIMS Patients with chronic liver disease (CLD) frequently develop reduced bone mass and an increased risk of fragility fractures, making osteoporosis a major extrahepatic complication that affects long-term prognosis and quality of life. Although the association between CLD and osteoporosis is well recogni...

Wen-Jing Wang, Guang-Yu Liu, Burhan Yokus et al. · JHEP Reports · 0 citations