Pallavi P. Pilaka-Akella

Spatiotemporal isoform profiling identifies a central activator of microexon splicing in C. elegans

Dynamic alternative splicing programs drive tissue specification and organismal development. Here, we present the most comprehensive, tissue-resolved alternative splicing dataset in Caenorhabditis elegans to date, spanning three major tissue types from early embryogenesis to adulthood. We uncovered broad developmental...