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Author

Pallavi Surana

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Open access Aug 2026

PGViS: Personal Genome Variant interpretation Score for lung cancer genomes

Inherited lung cancer risk arises from both protein-coding and non-coding germline variants, but the functional non-coding component is largely uncharacterized. Genome-wide association studies and polygenic risk scores identify tag variants, not causal ones. Neither resolves which regulatory element is perturbed. DNA f...

Pallavi Surana, P. Dutta, Paolo Boffetta et al. · 0 citations

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