Author

Pamela C. Rosato

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Jul 2026

Repeated brain resident memory T cell reactivation induces microglial and T cell remodeling and sustained microglia activation in Alzheimer’s disease 2259954

This data reveals unique microglial and bTRM remodeling driven by repeated bTRM reactivation, suggesting an inflammatory role of bTRM in AD and providing insight into neuroimmune crosstalk that can guide AD immunotherapies.

Tiffany Chen, Hanna N. Degefu, Sierra A. Kleist et al. · Journal of Immunology · 0 citations

Open access Jul 2026

Robust T Cell Activation Kills Tumors Regardless of T Cell Specificity 2260126

Triggering productive T cell activation within tumors can be sufficient for immunotherapy, without needing to induce or rescue cancer-specific responses.

Tyler Dao, Noah V. Gavil, M. Geller et al. · Journal of Immunology · 0 citations

Open access Jul 2026

Glioblastoma Subtypes Exhibit Distinct Migration Mechanics and Immune Responses

Mesenchymal tumors have aggressive migration but are immunologically “hot,” which suppresses net proliferation and may explain the lack of a strong survival difference between subtypes clinically, while also opening up new opportunities for subtype-specific therapies.

Ghaidan A Shamsan, Chao J. Liu, B. Braman et al. · Cancer Research Communicatio... · 0 citations