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Exploring the therapeutic applications of metformin in articular cartilage repair: mechanistic insights and translational perspectives
Articular cartilage is characterized by an avascular structure and limited intrinsic regenerative capacity. The most prevalent pathological conditions that lead to cartilage damage are osteoarthritis (OA) and rheumatoid arthritis (RA). In recent decades, cartilage homeostasis has been shown to be particularly vulnerabl...