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Pan-Pan Jiang

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Open access Aug 2026

SGLT2 inhibition, uric acid and inflammation in glycemic burden-related progression of cardiac autonomic neuropathy in type 2 diabetes mellitus: insights from machine learning and mediation analysis

SGLT2 inhibitor use is significantly associated with a lower risk of DCAN deterioration in T2DM patients, whereas elevated HbA1c levels correlate with disease progression, potentially involving pathways of exacerbated uric acid metabolism and systemic inflammation.

Jing-Jing Wang, Jie Hu, Wu Dai et al. · 0 citations

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