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Abstract Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by persistent synovitis and progressive structural joint damage. Its pathology involves immune-cell infiltration, pannus formation, cartilage degradation, and bone destruction. Although autoantibodies, inflammatory cytokines, and aberrant...
Although higher HOMA-IR was inversely associated with mortality overall, subgroup-specific associations were heterogeneous and should not be interpreted as evidence of a protective effect of IR and should not be interpreted as evidence of a protective effect of IR.
The fusion enzyme AtSuSy-L12-UGT74AN1M2 via the iMARS platform is designed, enabling in situ UDP-glucose generation coupled with highly efficient BIA glycosylation and identifying promising candidates for drug development.
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