Sustainably Synthesized Small Molecule Therapeutic Aggregates Attenuate Aβ-Induced ROS-Mitochondrial-Apoptotic Cascade in Alzheimer's Disease.
Alzheimer's disease (AD) is characterized by amyloid-β (Aβ) aggregation, oxidative stress, mitochondrial dysfunction, and progressive neuronal loss, yet effective disease-modifying therapeutics remain limited. Herein, we report the sustainable synthesis of two triphenylamine-based donor-acceptor (D-A) scaffolds, TPA-IM...