Open access
Aug 2026
Surfaceome CRISPR activation screening uncovers ligands regulating tumor sensitivity to NK cell killing
Natural killer (NK) cell-based immunotherapies are promising for cancer treatment due to their ability to eliminate cancer cells independently of antigen presentation and “off-the-shelf” utility. However, molecular determinants governing tumor susceptibility to NK cytotoxicity remain incompletely understood. Here we em...
Ravi K. Dinesh, Xiaotong Wang, Imran A. Mohammad et al.
· Nature Communications · 0 citations