Review
Open access
Aug 2026
Investigating the Mechanistic Role of piRNA Dysregulation in Amyloid-beta Toxicity and Tau Pathology in Alzheimer’s Disease Pathophysiology: Implications for Therapeutic Targets
This review synthesizes current knowledge regarding piRNA dysregulation in AD, examining mechanistic links between piRNA loss, transposable element activation, Aβ toxicity, and tau pathology while evaluating therapeutic implications.
S. Taherkhani, Zeynab Sharifiaghdam, Parnian Amani
· SVOA Neurology · 0 citations