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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Patricia Leroyer

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2 papers indexed here

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Open access Sep 2026

Key Molecular Parameters of PEI for Efficient DNA Delivery Into HEK293T Cells

The development of polyplexes from natural or synthetic polycations and nucleic acids remains limited by intracellular barriers, which restrict efficient protein expression. A fundamental understanding of how polymer molecular design influences these processes is therefore essential. Here, we investigate the relationsh...

Paulina Alejandra Montaño González, M. Rochedy, Christophe Schatz et al. · 0 citations
Open access Sep 2026

Influence of the lipid thioether modification and formulation method on lipoplex structure, stability and transfection efficiency in HEK293T cells.

Lipoplexes, formed by electrostatic interactions between nucleic acids and cationic lipids, must protect their cargo, enable cellular uptake and promote intracellular release for non-viral gene delivery. Although traditionally produced by bulk complexation, scalable microfluidic methods are now available. However, how...

M. Rochedy, Laurie Dechamboux, A. Dupont et al. · 0 citations

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