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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Patrick Orlando

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2 papers indexed here

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Review Open access Oct 2026

Sulforaphane as a Therapeutic Target for Sarcopenia in Type 2 Diabetes: Mechanistic Insights and Translational Evidence

Sulforaphane, a bioactive isothiocyanate abundant in cruciferous vegetables, has emerged as a potential multi-target therapeutic agent capable of mitigating these pathological processes. Here, using evidence from preclinical and clinical literature, we review the mechanistic and translational evidence linking sulforaph...

Ayanda Ngcobo, S. Shabalala, Nokulunga Hlengwa et al. · 0 citations
Oct 2026

A soluble form of 5-methyltetrahydrofolate modulates UVA-induced oxidative stress and cellular recovery processes in human dermal fibroblasts.

One-carbon metabolism supports nucleotide synthesis and methylation reactions, which are fundamental for cellular homeostasis and repair. The biologically active folate 5-methyltetrahydrofolate (5-MTHF) may help counteract UVA-induced stress in human dermal fibroblasts (HDF) and support their recovery. To test this hyp...

Alessia Luccarini, Sara Barbarossa, Patrick Orlando et al. · 0 citations

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