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Matrix Vesicle Nanostructures Guide Spatially Organized Bone-Like Mineralization in Biomimetic Collagen Scaffolds.
Bone formation is tightly regulated by osteoblasts, which secrete extracellular matrix (ECM) components and heterogeneous populations of extracellular vesicles (EVs). Among EVs, matrix vesicles (MVs) are uniquely associated with mineralization and act as bioactive extracellular nanostructures that initiate and spatiall...
Coacervation-based co-encapsulation of curcumin and vitamin E in gelatine-alginate microcapsules: a comprehensive study on encapsulation efficiency, physical properties, structure and release behaviour.
Curcumin and α-tocopherol (vitamin E) are lipophilic antioxidants limited by poor stability. To overcome this, both compounds were co-encapsulated in tannic acid-crosslinked gelatine-sodium alginate microcapsules via complex coacervation, comparing Ultra-Turrax (UT) and ultrasonication (US) homogenisation across core-t...