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Author

Patrik Brundin

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Open access Sep 2026

α-Synuclein Seeding in Dopaminergic Neurons Transplanted into the Putamen of Parkinson’s Disease Patients

Healthy embryonic neurons grafted into the putamen of Parkinson’s disease (PD) patients start to develop Lewy pathology 10 years after transplantation. It remains unclear whether this pathology is initiated by the spread of host-derived α-synuclein (αsyn) aggregates which seed aggregation in the grafted cells or arises...

Jayda B. Duvernay, B. Killinger, Solji G. Choi et al. · 0 citations

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