Review
Open access
Oct 2026
Silencing without clearing: pharmacological modulation of the SASP in aging and disease
The global rise in life expectancy has led to an increasing prevalence of age-related diseases, including neurodegenerative disorders, cancer, type 2 diabetes mellitus, and cardiovascular conditions, placing substantial societal and economic burdens on healthcare systems worldwide. A key mechanism underlying both aging...
Lukas Fresser, Zofia Chrienova, Jan Gebrt et al.
· Frontiers in Pharmacology · 0 citations