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Paul J. Baker

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Open access Jul 2026

Protein kinase F regulates the virulence of Mycobacterium tuberculosis

The data suggest that expression of PknF, as a modulator of multiple downstream effector proteins, restricts the virulence of Mtb in the lungs of mice through an NLRP3 inflammasome-independent mechanism, but potentially via suppressing production of the virulence lipid, PDIM.

Flor Torres-Juárez, Shivangi Rastogi, David C. Young et al. · 0 citations

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