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Author

Paul Sastourné

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Open access Jul 2026

Pan-cancer proteogenomic interrogation of the ubiquitin-proteasome system.

An integrated pan-cancer analysis of UPS protein dysregulation, prognostic associations, and mutation-driven remodeling shows that mRNA poorly predicts UPS protein abundance, that a defined set of E3 ligases is recurrently dysregulated across cancers, and that somatic mutations produce coherent UPS protein-quantitative...

Tania J. González-Robles, M. Khan, Paul Sastourné et al. · 0 citations

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