Dopamine D2 receptor dependent and independent structural, intrinsic and synaptic adaptations in experimental parkinsonism.
D2R signaling is identified as a major determinant of iMSN structural and intrinsic physiological integrity and global loss of D2R function reproduces many of the adaptations induced by dopamine depletion, indicating that dopamine depletion drives distinct forms of plasticity through separable D2R dependent and indepen...