Sirtuins (SIRTs) are a family of proteins involved in diverse cellular processes and play important roles in ageing and the development of osteoarthritis (OA). Among them, SIRT1, SIRT3, and SIRT6 have been identified as key regulators of cartilage homeostasis, primarily through their control of oxidative stress and mod...
Paweł Dec, Marek Dzik, Paulina Plewa et al.· European Cells & Materia...· 0 citations
Asthma is a chronic inflammatory airway disease characterized by considerable clinical and molecular heterogeneity, involving complex interactions between genetic susceptibility, environmental factors, and immune dysregulation. Increasing evidence indicates that non-coding RNAs (ncRNAs), including microRNAs (miRNAs), l...
Rheumatoid arthritis (RA) is a chronic autoimmune disease with a complex, multifactorial aetiology, in which both environmental factors and genetic predisposition play a significant role. This narrative review summarises the genetic polymorphisms associated with RA that have been identified by genome-wide association s...
Paulina Plewa, Hanna Ostałowska, Zuzanna Leciej et al.· Genes· 0 citations
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