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Pauline Funke

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Review Open access Oct 2026

Recent advances in understanding the regulatory mechanisms of P4-ATPase lipid flippases

Abstract P4-ATPases establish and maintain transbilayer lipid asymmetry in eukaryotic membranes by transporting phospholipids from the exoplasmic to the cytosolic membrane leaflet at the expense of ATP hydrolysis. In recent years, biochemical analysis together with an increasing number of cryo-electron microscopy struc...

Pauline Funke, Mathilde Roth, T. Dieudonné et al. · 0 citations

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