Anti-CD20 MONOCLONAL ANTIBODIES IN THE TREATMENT OF MULTIPLE SCLEROSIS: MECHANISMS OF ACTION, CLINICAL EFFICACY, SAFETY, AND CONTEMPORARY THERAPEUTIC PERSPECTIVES
Multiple sclerosis (MS) is a chronic immune-mediated disease of the central nervous system in which B lymphocytes play a central role in disease pathogenesis. The development of anti-CD20 monoclonal antibodies has transformed the therapeutic landscape of MS by providing highly effective disease-modifying therapies with...