Author

Pearly Ye

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Open access Aug 2026

Senescent microglia with shortened telomeres secrete soluble DLK1 to induce aging-associated hypomyelination and neuronal dysfunction.

Findings identify microglial senescence as a core consequence of telomere shortening and reveal sDLK1 as a microglia-derived senescence ligand that drives oligodendrocyte and neuronal dysfunction in aging.

Bangyan Liu, M. Mahoney, Yilin Feng et al. · Neuron · 0 citations