NIR-Triggered Hydroxyl Radical Storm: A Novel Phototherapy Nanoplatform for Potent Ferroptosis‑Like Cell Death Induction in Tumors.
This research develops an NIR-triggered organic photocatalyst that produces hydroxyl radical and photooxidates NADH and achieves antitumor efficacy in 4T1-bearing mouse models, highlighting the potential of employing an NIR-activated organic photocatalyst to integrate phototherapy with hydroxyl radical generation.