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Pei-Ni Chen

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Oct 2026

Acacetin Promotes Cell Death and Inhibits Migration in Follicular Thyroid Cells

Background/Aim: Distant metastasis and chemoresistance render the prognosis of follicular thyroid cancer (FTC) unsatisfactory. Acacetin, which is found in various traditional Chinese medicinal herbs, has been reported to exert antitumor effects. Herein, the molecular mechanisms of acacetin on the proliferation of FTC W...

Sheng-Tat Lee, Pei-Ni Chen, Ke-Min Chen et al. · 0 citations
Open access Aug 2026

ESM1-mediated DNMT3A suppresses cervical cancer metastasis through epigenetic regulation of ID3 expression

In vivo xenograft and experimental metastasis models validated that ESM1 depletion significantly impaired tumor growth and lung metastasis while increasing ID3 expression, identifying the ESM1/DNMT3A/ID3 axis as a novel epigenetic driver of cervical cancer and a potential therapeutic target.

Chen-Lin Yu, Chia-Liang Lin, Hsiang-Lin Lee et al. · 0 citations

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