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Pei-Shan Zhou

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Review Sep 2026

Metabolic reprogramming of myeloid antigen-presenting cells in the tumor microenvironment: mechanisms of antigen presentation failure and therapeutic opportunities.

Antigen-presenting cells (APCs) translate tumor-derived signals into adaptive immune responses, yet their function is shaped by the metabolically hostile tumor microenvironment (TME). Hypoxia, acidosis, nutrient scarcity, and immunoregulatory metabolite accumulation can reprogram myeloid APC metabolism, impair antigen...

Pei-Shan Zhou, Yi-Cun Han, Qing Ji · 0 citations

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