Tumor Microenvironment-Triggered Nanocrystal-to-Nanocrystal Transformation for RNA-Boosted Photo-STING Therapy.
2TZP, a photosensitizer engineered with a synergistic proton-capturing motif that confers a narrow pH response range within the TME, demonstrates a model of NCNC transformation within the TME, and establishes a design principle to couple structural regulation with dynamic, on-demand function amplification for potential...