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Author

Peilin Jin

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Open access Aug 2026

Single-cell and spatial transcriptomics characterisation of RSPO2+ nucleus pulposus cells reveals a WNT/FN1–CD44 degenerative axis and therapeutic targets in IVDD

This study identifies an RSPO2-associated NP state and a candidate WNT/FN1–CD44 programme linked to IVDD, and provides a testable basis for future WNT-directed intervention studies while recognising the limits of acute rat models and cross-species data.

Qiu-Wei Li, Guoyan Liang, Kai-Da Bo et al. · 1 citation
Open access Jul 2026

Hounsfield unit measurements from different regions of interest in lumbar spine CT: correlation with DEXA-derived bone mineral density and fracture status.

Different lumbar CT ROI methods demonstrated comparable performance in assessing BMD and discriminating thoracolumbar fragility fracture status, and sensitivity analysis confirmed that exclusion of substituted vertebral levels did not materially affect the results.

Zengkai Zhou, Jia-Qi Wang, Lu-Ping Zhou et al. · 0 citations

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