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Peng-Hao Xu

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Open access Sep 2026

LucaCell: a sequence-centric foundation model for cross-species single-cell analysis

LucaCell, a sequence-centric foundation model that represents genes through pre-trained mRNA sequence embeddings rather than static gene annotations, is presented, showing that sequence-informed gene representation can improve the generalization of single-cell foundation models across species, data types, and predictiv...

Yan Sun, Yong He, Min-Si Ren et al. · 0 citations

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